Significant mobilization of both conventional and regulatory T cells with AMD3100
نویسندگان
چکیده
منابع مشابه
HEMATOPOIESIS AND STEM CELLS Significant mobilization of both conventional and regulatory T cells with AMD3100
1Department of Pediatrics, Children’s Healthcare of Atlanta and the Emory Transplant Center, Emory University School of Medicine, Atlanta, GA; 2Department of Microbiology and Immunology, Uniformed Services University of Health Sciences, Bethesda, MD; 3Emory Transplant Center, Department of Surgery, Emory University School of Medicine, Atlanta, GA; 4Hematology Branch, National Heart, Lung, and B...
متن کاملSignificant mobilization of both conventional and regulatory T cells with AMD3100.
In this study, we used the rhesus macaque model to determine the impact that AMD3100 has on lymphocyte mobilization, both alone and in combination with G-CSF. Our results indicate that, unlike G-CSF, AMD3100 substantially mobilizes both B and T lymphocytes into the peripheral blood. This led to significant increases in the peripheral blood content of both effector and regulatory T-cell populati...
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ژورنال
عنوان ژورنال: Blood
سال: 2011
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2011-06-359331